Substrate: NF-kappa-B essential modulator (Serine/threonine kinase)
Seq-ID: O88522 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
MINT-7262667   UBIQ_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
metal ion binding nucleus transcription,
activation of NF-kappaB-inducing kinase activity,
B cell homeostasis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 369 PPLLPAPAHHSFHLALSNQRR IKK_group 11971901
LTP
1.00
 - -
0.61
 - medium
S 375 PAHHSFHLALSNQRRSPPEEP IKK_beta 11971901
LTP
0.49
 - -
0.73
 - medium

Substrate: NF-kappa-B essential modulator (Serine/threonine kinase)
Seq-ID: Q9Y6K9 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-15857   TNAP3_HUMAN
MINT-16075   RIPK1_HUMAN
MINT-16575   RIPK2_HUMAN
MINT-47843   IKBA_HUMAN
MINT-47855   IKBB_HUMAN
MINT-48127   SYVC_HUMAN
MINT-48129   GOGA3_HUMAN
MINT-48131   HS71L_HUMAN
MINT-48132   GRP78_HUMAN
MINT-48133   DREB_HUMAN
MINT-48134   HSP7C_HUMAN
MINT-48137   IKKA_HUMAN
MINT-48140   ADT2_HUMAN
MINT-48142   GRP75_HUMAN
MINT-48144   SYMC_HUMAN
MINT-48146   RS10_HUMAN
MINT-48147   RLA2_HUMAN
MINT-48149   XPO1_HUMAN
MINT-48151   MYO1C_HUMAN
MINT-48152   EPIPL_HUMAN
MINT-48153   RS3_HUMAN
MINT-48154   TIF1B_HUMAN
MINT-48156   RS20_HUMAN
MINT-48157   KINH_HUMAN
MINT-48158   CDC37_HUMAN
MINT-48159   SYIC_HUMAN
MINT-48160   GBLP_HUMAN
MINT-48161   EF1A2_HUMAN
MINT-48162   MSH2_HUMAN
MINT-48166   MCM7_HUMAN
MINT-48167   MYH10_HUMAN
MINT-48168   PYR1_HUMAN
MINT-48169   CALX_HUMAN
MINT-48170   ACTG_HUMAN
MINT-48171   ESYT1_HUMAN
MINT-48173   CLH1_HUMAN
MINT-48174   IKKB_HUMAN
MINT-48177   RS14_HUMAN
MINT-48181   DYHC1_HUMAN
MINT-48186   CALM_HUMAN
MINT-48187   UTP20_HUMAN
MINT-48188   RLA0_HUMAN
MINT-48190   HS90A_HUMAN
MINT-48192   FAS_HUMAN
MINT-48193   TBB5_HUMAN
MINT-48195   ECM29_HUMAN
MINT-48196   TBB4_HUMAN
MINT-48198   RS27_HUMAN
MINT-48199   A16L1_HUMAN
MINT-48204   KCC2D_HUMAN
MINT-48205   USO1_HUMAN
MINT-48206   1433Z_HUMAN
MINT-48207   FLNA_HUMAN
MINT-48208   IPO7_HUMAN
MINT-48209   SMC4_HUMAN
MINT-48213   GCN1L_HUMAN
MINT-48214   MYH9_HUMAN
MINT-48215   HNRPU_HUMAN
MINT-48218   VIME_HUMAN
MINT-48220   PARP1_HUMAN
MINT-48221   ADT3_HUMAN
MINT-48222   CCAR1_HUMAN
MINT-48223   COPA_HUMAN
MINT-48224   TBK1_HUMAN
MINT-48225   PP1G_HUMAN
MINT-48226   PP1B_HUMAN
MINT-48227   TXLNA_HUMAN
MINT-48228   PUR2_HUMAN
MINT-48229   PRKDC_HUMAN
MINT-48230   MYL6_HUMAN
MINT-48232   XPO7_HUMAN
MINT-48235   RS3A_HUMAN
MINT-48239   HS90B_HUMAN
MINT-48240   ML12A_HUMAN
MINT-48241   CH60_HUMAN
MINT-48244   SET_HUMAN
MINT-48245   MYO1D_HUMAN
MINT-48371   M3K3_HUMAN
MINT-48638   NFKB1_HUMAN
MINT-48692   NFKB2_HUMAN
MINT-48784   M3K14_HUMAN
MINT-2844414   SQSTM_HUMAN
MINT-4652797   M3K7_HUMAN
MINT-6177604   MALT1_HUMAN
MINT-6978609   ATM_HUMAN
MINT-6978686   ATR_HUMAN
MINT-6978719   ATRIP_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein domain specific binding,
metal ion binding,
signal transducer activity		 nucleus transcription,
immune response,
interspecies interaction between organisms,
positive regulation of NF-kappaB transcription factor activity,
response to DNA damage stimulus,
T cell receptor signaling pathway,
induction of apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 31 AADQDVLGEESPLGKPAMLHL IKK_beta 12657630
LTP
1.00
 - -
0.67
 --
S 43 LGKPAMLHLPSEQGAPETLQR IKK_beta 12657630
LTP
1.00
 - -
0.64
 --
S 85 RCEELLHFQASQREEKEFLMC ATM 16497931
LTP
0.89
 MOD_PIKK_1
 - COIL
0.30
 3BRV 56.56%
S 376 APLPPAPAYLSSPLALPSQRR IKK_beta 12657630
LTP
1.00
 - -
0.62
 --
S 377 PLPPAPAYLSSPLALPSQRRS - 18669648
HTP
0.04
 - -
0.65
 --
S 387 SPLALPSQRRSPPEEPPDFCC - 18669648
HTP
1.00
 - -
0.61
 --

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